Melatonin B12Advanced Repair Serum
Dermatologist tested. Suitable for all skin types. Incorporates easily into your face care routine.
“Melatonin is a modulator of the circadian rhythm, which means that it plays an important role in supporting the skin’s natural repair and renewal. Vitamin B12 enhances the activity of melatonin further, and also supports DNA repair.” – Dr. Marko Lens
- Helps maximise the skin’s natural repair
- Reinforces the skin’s protective barrier
- Reduces visible signs of skin ageing, tiredness and stress
Use daily, morning and evening. Apply 2 to 3 pumps to face, neck, and décolleté. Follow with the next step in your skincare routine.
Base: A completely natural, plant-derived gel complex with multiple lamellar structure that mimics the skin’s natural lipids (lipid bilayer). Provides intense moisture to the skin, enhances skin barrier function and acts as a ‘second skin’.
Melatonin: A modulator of the circadian rhythm that plays an important role in the process of skin repair and renewal. Demonstrates excellent antioxidant activity and provides anti-inflammatory support.
Vitamin B12 (Cyanocobalamin): A synthetic form of vitamin B12. Plays an important role in energy production, cell metabolism and DNA repair. The latest research findings show that vitamin B12 enhances the activity of melatonin.
Glutamylamidoethyl Imidazole: A chronopeptide that mimics sun exposure activation of the circadian genes. Helps to resynchronise circadian rhythm, optimise vitamin D activity and enhance natural skin defences. Promotes skin renewal and reduces the appearance of wrinkles.
Acetyl Tetrapeptide-2: A peptide composed of 4 amino acids. Enhances the expression of genes involved in the organization of elastic fibres and dermal cohesion.
Hexapeptide-3: A peptide composed of 6 amino acids. Enhances dermal repair and regeneration.
Glycosaminoglycans: Polysaccharides naturally present in the skin as major components of the extracellular matrix. Exhibit excellent moisturizing and skin regenerating properties. Supports the collagen network by inhibiting matrix metalloproteinase (MMP), enzymes responsible for collagen degradation. Increases skin resistance to physical damage and enhances skin barrier function. Clinical studies have shown that glycosaminoglycans reduce the appearance of dark circles, rosacea and skin redness.
Phospholipids: Major building components in the structure of cellular membranes. These natural, skin-identical ingredients demonstrate excellent moisturising, repairing and protective properties.
Panthenol: A provitamin of vitamin B5. Used as an emollient due to excellent moisturising and conditioning properties. Clinical studies have shown that panthenol reduces inflammation and itching, provides soothing effect and promotes wound healing.
Dimethicone: A synthetic polymer molecule with excellent emollient, conditioning and skin protecting properties. Fills in fine lines and wrinkles and gives the skin a plumper look.
Irish moss (Chondrus crispus): An extract from red algae (seaweed) rich in polysaccharide carrageenan. Possesses excellent water binding, moisturising, film-forming, soothing and antioxidant properties.
Ornithine: An amino acid encapsulated in ionosomes. By activation or up regulation of the transcription factor HIF-1 (Hypoxia Inducible Factor), ornithine restores fatty tissue volume and exhibits a lipofilling-like effect.
Proline: An amino acid used as a building block in the production of proteins. Increases collagen production, improves skin elasticity and promotes skin repair and regeneration.
Sodium PCA: A sodium salt of PCA (pyroglutamic acid), a naturally occurring component of human skin and a part of NMF (natural moisturising factors). Used as humectants due to excellent moisturising, conditioning and water-absorbing properties.
Beta-Glucan: A yeast-derived polysaccharide with multiple actions: antioxidant, anti-inflammatory and skin-soothing. Enhances natural defence mechanisms, boosts cellular respiration and promotes natural repair process and wound healing.
Lecithin: A vegetable-based phosphatidylcholine, a natural part of all cell membranes. Shows emollient, moisturising and smoothing properties.
Glycolipids: Biomimetic lipid molecules with restructuring, repairing and protective properties. Strengthen the barrier function and boost the hydro-retaining capacity of the skin.
Vegetable protein: A plant-derived protein with moisturising and skin-conditioning properties. Enhances collagen production and promotes skin firmness and elasticity.
Yeast: An extract of yeast and a filtrate of the lysate (the solution consisting of the material released from cell lysis; cellular disruption) obtained by the fermentation of yeast (Saccharomyces). Rich in amino acids, essential minerals, beta-glucan and vitamins. Yeast possesses anti-inflammatory, revitalising and protective properties. Increases cell respiration and metabolism, stimulates oxygen consumption and enhances skin repair.
Phyto-melatonin complex: A proprietary complex of plants rich in melatonin. This unique botanical blend includes thyme (Thymus vulgaris), sage (Salvia officinalis) and yarrow (Achillea millefolium). Studies show that plant-derived melatonin has excellent antioxidant properties with important actions in the control of reactive oxygen and nitrogen species (ROS and RNS).
Lespedeza (Lespedeza capitata): An extract from the leaf/stem of the lespedeza plant. Helps to resynchronise a circadian rhythm deregulated by environmental factors and stressful lifestyles, combat signs of fatigue and improve skin complexion.
Hyaluronic Acid: A full spectrum of different molecular weights (very low, low and medium) of pure hyaluronic acid working in synergy. Shows multiple activities: improves skin moisture, strengthens barrier function, helps to retain and maintain skin elasticity, reduces the appearance of fine lines and wrinkles and restores skin suppleness.
Adenosine triphosphate (ATP): A major source of intracellular energy. Promotes natural skin repair to help reduce visible signs of aging.
Adenosine monophosphate (AMP): A source of intracellular energy. Shows energising, repairing and skin-conditioning properties.
Uracil: One of the four nucleobases of RNA. Helps carry out the synthesis of many enzymes necessary for cell function. Enhances skin revitalisation and repair.
Guanosine: A nucleoside comprising guanine attached to a ribose. Shows anti-inflammatory activity and promotes cell repair.
Aloe Vera (Aloe barbadensis): The juice obtained from the leaf of aloe shows multiple properties: moisturising, anti-inflammatory, anti-bacterial, antioxidant, soothing and wound healing.
Rice (Oryza sativa): Rice has been used for centuries to improve the skin’s appearance and achieve a flawlessly silky complexion. It is rich in B-complex vitamins, vitamin E and gamma oryzanol. Rice has excellent moisturising, regenerative, smoothing, revitalising and anti-inflammatory properties.
Polyglutamic acid: Derived from Japanese soybeans fermented with Bacillus subtilis (natto). Demonstrates excellent moisturising properties and enhances skin elasticity.
Sodium Hyaluronate: A salt of hyaluronic acid (HA). HA improves skin moisture, strengthens barrier function, helps to retain and maintain skin elasticity, reduces the appearance of fine lines and wrinkles and restores skin suppleness.
Pomegranate (Punica granatum): Pomegranate seed extract is rich in vitamin C and shows excellent antioxidant, anti-inflammatory, brightening and regenerative properties.
Rosemary (Rosmarinus officinalis): Rosemary leaf extract is rich in rosmarinic acid, carnosic acid, caffeic acid, ursolic acid and betulinic acid. Demonstrates multiple beneficial properties: antioxidant, anti-bacterial, anti-septic, anti-inflammatory, astringent, toning and healing.
Blue Agave (Agave tequilana): The extract from the leaf of the agave plant shows film-forming properties, provides an instantly visible ‘lifting’ effect and reduces the appearance of fine lines and wrinkles.
Glycerin: A vegetable-derived molecule naturally present in the skin. Acts an excellent humectant, a substance that attracts moisture from the environment and increases the amount of water in the surface layers of the skin.
Vitamin E (Tocopherol): A naturally derived vitamin with powerful antioxidant and photoprotective properties. Tocopherol is an excellent moisturiser that helps to reduce water loss and strengthen the skin’s natural barrier.
Acetyl tyrosine: An acetylated form of non-essential amino-acid L-Tyrosine. Shows skin-conditioning properties.
Dextran: A polysaccharide composed of multiple glucose molecules. Possesses water-binding, moisturising and soothing properties.
Plant-derived esters: A blend of 2 esters (Apricot Kernel Oil Polyglyceryl-6 Esters and Polyglyceryl-10 Dipalmitate) made from raw materials of 100% plant origin. Possesses excellent emollient, skin-conditioning and protective properties.
Algin (Alginic acid): A polysaccharide derived from brown algae. Demonstrates excellent water-binding properties. Used to enhance product thickness and texture.
Caprylic/Capric Triglyceride: An ester derived from coconut oil and glycerin. Shows excellent emollient, moisturising and skin-replenishing properties.
Full list of ingredients: AQUA (WATER), GLYCERIN, BUTYLENE GLYCOL, PROPANEDIOL, HYDROLYZED GLYCOSAMINOGLYCANS, BENZYL ALCOHOL, BEHENYL ALCOHOL, GLYCERYL STEARATE, PHOSPHOLIPIDS, PANTHENOL, DIMETHICONE, PALMITIC ACID, STEARIC ACID, CHONDRUS CRISPUS (CARRAGEENAN) EXTRACT, APRICOT KERNEL OIL POLYGLYCERYL-6 ESTERS, ORNITHINE, PROLINE, SODIUM PCA, BETA-GLUCAN, MELATONIN, LECITHIN, GLYCOLIPIDS, HYDROLYZED VEGETABLE PROTEIN, HYDROLYZED YEAST EXTRACT, POLYGLYCERYL-10 DIPALMITATE, ACETYL TETRAPEPTIDE-2, HEXAPEPTIDE-3, ACHILLEA MILLEFOLIUM EXTRACT, THYMUS VULGARIS (THYME) LEAF EXTRACT, SALVIA OFFICINALIS (SAGE) LEAF EXTRACT, LESPEDEZA CAPITATA LEAF/STEM EXTRACT, HYALURONIC ACID, ADENOSINE TRIPHOSPHATE, SACCHAROMYCES FERMENT LYSATE FILTRATE, ADENOSINE PHOSPHATE, GUANOSINE, URACIL, CYANOCOBALAMIN, ORYZA SATIVA (RICE) EXTRACT, ALOE BARBADENSIS LEAF JUICE, POLYGLUTAMIC ACID, SODIUM HYALURONATE, PUNICA GRANATUM SEED EXTRACT, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, GLUTAMYLAMIDOETHYL IMIDAZOLE, AGAVE TEQUILANA LEAF EXTRACT, TOCOPHEROL, ACETYL TYROSINE, LAURYL ALCOHOL, MYRISTYL ALCOHOL, CETYL ALCOHOL, CARBOMER, MALTOSE, 1,2-HEXANEDIOL, DEHYDROACETIC ACID, DEXTRAN, SODIUM DEHYDROACETATE, DIETHYLHEXYL SYRINGYLIDENEMALONATE, SODIUM HYDROXIDE, CITRIC ACID, HYDROXYACETOPHENONE, SORBITAN OLEATE, ALGIN, XANTHAN GUM, BENZOIC ACID, LEVULINIC ACID, p-ANISIC ACID, CAPRYLIC/CAPRIC TRIGLYCERIDE, SORBIC ACID, SODIUM BENZOATE, POTASSIUM SORBATE.
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